Immobilization of biologically active proteins with a polypeptid

Details Immobilization of biologically active proteins with a polypeptid Immobilization of biologically active proteins with a polypeptid

1974-10-29

1976-10-12

Naff, David M.

Textiles: fiber preparation

195 63, 195DIG11, 260112R, 2601125R, C07G 702

Patent

active

039856178

ABSTRACT:
Immobilized biologically active proteins such as enzymes having high activity and stability are prepared by covalent bonding of the biologically active protein to an azide derivative of a polypeptide such as polymethylglutamate of which at least one carboxyl group in a side chain is converted to a carboxyl azide group.

REFERENCES:
patent: 3574062 (1971-04-01), Sato
patent: 3705084 (1972-12-01), Reynolds
patent: 3843446 (1974-10-01), Vieth et al.
Julliard et al., Some Modifications of the Kinetic Properties of Bovine Liver Glutamate Dehydrogenase (NADCP) Covalently bound to a Solid Matrix of Collagen, FEBS Letters, vol. 14, No. 3, 1971, (pp. 185-188).
Zaborsky, O., Immobilized Enzymes, CRC Press, Cleveland, Ohio, 1973, (pp. 28-30).
Mitz et al., Synthesis of Biologically Active Cellulose Derivatives of Enzymes, Nature, vol. 189, 1961, (pp. 576-577).

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