Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-03-03
1995-05-30
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 63, 548110, 5483381, 5483401, 5483415, A61K 31415, C07D23368, C07D23360
Patent
active
054201497
ABSTRACT:
Imidazolyl-substituted phenylacetic acid derivatives are prepared by first reacting suitably substituted phenylacetic acid with imidazoles and subsequently converting the product into an amide. The compounds can be employed as active compounds in medicaments, in particular for treating hypertension and atherosclerosis.
REFERENCES:
patent: 4355040 (1982-10-01), Furukawa et al.
patent: 4946841 (1990-08-01), Baader et al.
Hollenberg, Journal of Medicinal Chemistry, vol. 33, No. 5, 1312-1329 (1990).
R. V. Vitzgert, Uspekhi, Khimii 32, 1-20 (1963).
R. Ross, J. Cell, Biol. 50, 172-186 (1971).
J. C. Sheehan, et al., J. Am. Chem. Soc. 95, 875-879 (1973).
N. L. Benoiton, et al., Int. Pept. Prot. Res. 17, 197-204 (1981).
N. Bartlett et al., J. Chem. Soc., Chem. Commun., (2), 167-168 (1966).
Frerman et al, J. Biol. Chem. 258, 7087-7093 (1983).
Beuck Martin
Dressel Jurgen
Fey Peter
Hanko Rudolf
Husch Walter
Bayer Aktiengesellschaft
Morris Patricia L.
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