Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-03-07
1978-03-21
Jiles, Henry R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602393B, 424269, C07D48704
Patent
active
040803236
ABSTRACT:
The present invention concerns compounds of the formula ##STR1## wherein X is hydrogen or halogen; R.sub.1 is hydrogen, halogen or trifluoromethyl; R.sub.2 is hydrogen or lower alkyl; and R.sub.3 is hydrogen, --COO lower alkyl or CON(R.sub.4).sub.2 wherein R.sub.4 is lower alkyl or hydrogen and may be different
And the pharmaceutically acceptable salts thereof.
Also provided are methods for the preparation of these compounds as well as pharmaceutical formulations which contain the active compounds of this invention. The compounds of the formula illustrated above are useful as anxiolytics, anticonvulsants, muscle relaxants and sedative agents.
REFERENCES:
chow et al. "J. Heterocyclic Chem." (1976), vol. 13, No. 1, pp. 163-164.
Fryer Rodney Ian
Walser Armin
Bond Robert T.
Gould George M.
Hoffman Frank P.
Hoffmann-La Roche Inc.
Jiles Henry R.
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