Imidazo[1,5-a][1,4]benzodiazepines

Details Imidazo[1,5-a][1,4]benzodiazepines Imidazo[1,5-a][1,4]benzodiazepines

1978-07-27

1979-03-27

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548324, C07D48704

Patent

active

041467221

ABSTRACT:
Compounds are disclosed of the formula ##STR1## wherein R.sub.1 is hydrogen, halogen or trifluoromethyl; R.sub.2 is selected from the group consisting of lower alkylthio together with the sulfoxide and sulfone thereof, halo, lower alkylamino or lower alkoxy; Y is oxo or thio; R.sub.3 is selected from the group consisting of hydrogen, --COOR.sub.4 wherein R.sub.4 is hydrogen or lower alkyl, --CONR.sub.6 R.sub.5 wherein R.sub.5 and R.sub.6 are hydrogen or lower alkyl; X is hydrogen or halogen; and R.sub.7 is lower alkyl or hydrogen and the pharmaceutically acceptable salts and N-oxides thereof.
Also presented are processes to produce the above compounds and intermediates therefor and derivatives thereof.

REFERENCES:
patent: 3763179 (1973-10-01), Gall
patent: 3852461 (1974-12-01), Hester, Jr. et al.

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