Imidazo [1,2-a] pyridines and their pharmaceutical use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

546121, A61K 3144, A01N 4342, C07D47102

Patent

active

055740421

ABSTRACT:
The invention relates to novel bradykinin antagonists of the formula: ##STR1## wherein R.sup.1 is halogen,

REFERENCES:
patent: 4450164 (1984-05-01), Bristol et al.
patent: 4507294 (1985-03-01), Bristol et al.
patent: 4725601 (1988-02-01), Ueda et al.
patent: 4782055 (1988-11-01), Ueda et al.
patent: 4831041 (1989-05-01), Shiokawa et al.
patent: 5212182 (1993-05-01), Musser et al.
J. Med. Chem., vol. 28, pp. 876-892, 1985, J. Kaminski, et al., "Antiulcer Agents. 1. Gastric Antisecretory and Cytoprotective Properties of Substituted Imidazo[1,2-a]Pyridines".
Chemical Abstracts, vol. 109, No. 7, Aug. 15, 1988, AN 48452v, SU-A-991 716, Dec. 30, 1987.

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