Imidazo[1,2-A]pyridine compounds as VEGF-R2 inhibitors

Details Imidazo[1,2-A]pyridine compounds as VEGF-R2 inhibitors Imidazo[1,2-A]pyridine compounds as VEGF-R2 inhibitors

2006-02-23

2010-02-23

Padmanabhan, Sreeni (Department: 1627)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S121000, C546S272700, C546S273100

Reexamination Certificate

active

07666879

ABSTRACT:
The present invention provides compounds that are inhibitors of VEGF-R2 of the formula: (I) and methods of using these compounds.

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Pargellis, Christopher, Inhibition of p38 MAP Kinase by Utilizing a Novel Allosteric Binding Site, Nature Structural Biology, 2002, 9(4), p. 268-272.
Wu, Zhicai, Design and Synthesis of 3,7-diarylimidazopyridines as Inhibitors if the VEGF-receptor KDR, Bioorganic & Medicinal Chemistry Letters, 14, 2004, p. 909-912.

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