IGF-1R inhibitor

Details IGF-1R inhibitor IGF-1R inhibitor

2006-01-27

2009-10-20

Shiao, Rei-Tsang (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C544S140000, C544S371000, C546S199000, C514S234500, C514S254060, C514S322000, C514S406000

Reexamination Certificate

active

07605272

ABSTRACT:
The present invention provides a type I insulin-like growth factor receptor (IGF-1R) inhibitor comprising, as an active ingredient, an indazole derivative represented by Formula (I):{wherein R1represents —NR4R5[wherein R4represents a hydrogen atom or the like, R5represents substituted or unsubstituted lower alkyl, —C(═O)R6(wherein R6represents substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl or the like), or the like], or the like, and R2and R3may be the same or different and each represents a hydrogen atom, hydroxy, substituted or unsubstituted lower alkoxy, or the like} or a pharmaceutically acceptable salt thereof, and the like.

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