Hypotensive sulphonamidopiperidyl indoles

Details Hypotensive sulphonamidopiperidyl indoles Hypotensive sulphonamidopiperidyl indoles

1976-09-23

1978-12-26

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546201, A61K 31445, C07D40106

Patent

active

041316800

ABSTRACT:
This invention relates to compounds having the general formula: ##STR1## WHEREIN W represents a phenyl or indolyl radical, either of which radicals may be unsubstituted or substituted by halogen, lower alkyl, lower alkoxy or hydroxy. A represents a lower alkylene radical, an oxo lower alkylene radical or a hydroxy lower alkylene radical; R represents a phenyl radical optionally substituted by halogen, lower alkyl, lower alkoxy or hydroxy, a cycloalkyl radical of 5 to 7 carbon atoms or a lower alkyl radical; R.sup.1 represents hydrogen or a lower alkyl radical or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof; which possess hypotensive activity.

REFERENCES:
patent: 3472870 (1969-10-01), Larsen et al.
patent: 3869463 (1975-03-01), Archibald
patent: 3936464 (1976-02-01), Allen et al.
patent: 4046900 (1977-09-01), Helsley et al.

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