Hypolipidemic 1,4-benzothiazepine-1,1-dioxides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

540552, A61K 3155, C07D28110, C07D41712

Patent

active

061143227

ABSTRACT:
The present invention is concerned with new hypolipidemic compounds, with processes and novel intermediates for their preparation, with pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions, such as atherosclerosis.
Compounds of the formula (I): ##STR1## wherein R.sup.1 to R.sup.10 and X are as defined in the Specification and useful as hypolipidemic compounds.

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patent: 5723458 (1998-03-01), Brieaddy et al.
patent: 6020330 (2000-02-01), Enhsen
Grundy, "Cholesterol and Coronary Heart Disease," JAMA, vol. 256, No. 20, pp. 2849-2858, Nov. 28, 1986.
P. Tyle, Review, "Iontophoretic Devices for Drug Delivery," Phaarmaceutical Research, vol. 3, No.6, pp. 318-326, 1986.

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