Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-07-25
1979-12-04
Demers, Arthur P.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2603405R, 542429, 542430, 542431, 542433, 542447, 542449, 424252, C07D31748, C07D40708
Patent
active
041772717
ABSTRACT:
Hydroxy- and oxo-substituted .alpha.-benzylidenylcycloalkanes having the formula: ##STR1## Z.sub.1, Z.sub.2 and Z.sub.3 each denotes a methoxy group or Z.sub.1 or Z.sub.2 and Z.sub.3 together denote a methylenedioxy group, and Z.sub.3 is a hydrogen atom or chlorine atom, one of the symbols R.sub.1 and R.sub.2 denotes a hydrogen atom and the other denotes a hydroxyl group or, together the two denote an oxygen atom; R.sub.3 denotes a hydrogen atom or a methyl group; R.sub.4 denotes a hydrogen atom, a methyl group or an aminomethyl group, the amino group being a dimethylamino, diethylamino, morpholino, 4-methyl-piperazino or piperidino radical; or R.sub.3 and R.sub.4 together denote a piperonylidene group; R.sub.5 denotes a hydrogen atom or a methyl group, and A forms, with the carbon atoms to which it is attached, a cyclopentane, cyclohexane, indane, tetrahydronaphthalene, perhydronaphthalene or piperidine structure and the pharmaceutically acceptable addition salts of the compounds containing an amino group.
The compounds have pharmacological activity on the central nervous system.
REFERENCES:
patent: 3468881 (1969-09-01), Szmuszkovicz
Swoboda et al., "Phytochemical Studies", in J.C.S., vol. C #2, 1967, pp. 161, 162.
Demers Arthur P.
Unicler
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