Hydrophile adhesive mass

Surgery: splint – brace – or bandage – Bandage structure – Skin laceration or wound cover

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Details

602 48, 428355, 424443, 128156, A61F 1300

Patent

active

060517484

DESCRIPTION:

BRIEF SUMMARY
FIELD OF THE INVENTION

The present invention relates to novel hydrophilic adhesive masses based on a block copolymer of the poly(styrene/olefin/styrene) type and on a hydrocolloid, with which an acrylate polymer is associated for increasing the absorption capacity of the hydrocolloid. The invention further relates to the use of these novel adhesive masses for medical purposes, in particular for the production of protective dressings and especially anti-blister dressings and dressings for the treatment of superficial dermo-epidermal lesions, exudative wounds and burns.


PRIOR ART

Numerous hydrophilic adhesive masses employed in these various medical applications have already been described. Examples which may thus be mentioned are patent applications FR-A-2,495,473, EP-A-130,061, EP-A-092,999 and EP-A-302,536 and U.S. Pat. No. 3,972,328.
The hydrophilic adhesive masses described in these documents are formed principally of an adhesive elastomer selected from polymers such as polyisobutenes or poly(styrene/olefin/styrene) block copolymers, for example poly(styrene/isoprene/styrene) or poly(styrene/ethylene/butylene/styrene), which may or may not be associated with so-called "tackifying" resins, plasticizers etc., and of one or more hydrocolloids.
The adhesive elastomer of a hydrophobic nature makes it possible to give the mass properties of elasticity, deformation or shock absorption (for example in an anti-blister dressing) but also of cohesion sufficient to prevent the adhesive from flowing out of the mass and allow ease of handling. However, it is incapable of absorbing liquids, so the resulting products do not easily stick to wet skin and do not stick, or quickly become unstuck, as soon as perspiration or exudates are absorbed.
By virtue of its hydrophilic character, the hydrocolloid gives these adhesive masses their properties of absorbing water, perspiration, liquids or exudates. However, it then has a tendency to swell, causing a loss of cohesion and meaning that the dressing comes apart when removed or is even lost.
Associating the properties of the adhesive elastomer with those of the hydrocolloid does not suffice to satisfy the numerous and often contradictory demands which are made on such hydrophilic adhesive masses in the context of the above-mentioned medical applications. Furthermore, given that it is also necessary to take account of the possible combinations of the compounds making up the formulation of the mass, there is very little room to manoeuvre in the production, for medical purposes, of a hydrophilic adhesive mass which has a maximum absorption and a durable adhesion over time. Finally, these products are additionally subject to more specific constraints; for example, they have to stick to the skin but not to the wound, protect the wound but avoid the problems of irritation and maceration, etc.
The various formulations and the various specific additives for improving the efficacy of the adhesive elastomer/hydrocolloid couple proposed in the documents cited above illustrate the need for and the difficulty of optimising the absorption properties without detracting from the adhesion properties and while at the same time taking into account all the above-mentioned demands for obtaining more efficient products and widening the formulation possibilities.
However, none of the publications referred to above discloses or suggests the novel specific hydrophilic adhesive masses of the invention, which provide a novel, efficient and unexpected solution, in terms of both absorption and adhesion, to the demands and problems presented by the production of hydrophilic adhesive masses for medical purposes.


OBJECTS OF THE INVENTION

In the field of hydrophilic adhesive masses employed for medical purposes, it would therefore be desirable to find a novel technical solution making it possible to achieve a compromise between the above-mentioned demands.
According to a first aspect of the invention, it is proposed to provide a novel hydrophilic adhesive mass wherein an acrylate polymer is added to a

REFERENCES:
patent: 4367732 (1983-01-01), Poulsen et al.
patent: 4393080 (1983-07-01), Pawelchak et al.
patent: 5827528 (1998-10-01), Kubo et al.

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