Human tumor-associated antigen

Details Human tumor-associated antigen Human tumor-associated antigen

1997-02-28

2000-02-01

Scheiner, Toni R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2431, 435 6, 435 691, 435346, C07H 2104, C12Q 168

Patent

active

060204788

ABSTRACT:
The present invention provides a human tumor-associated antigen (PRAT) and polynucleotides which identify and encode PRAT. In addition, the invention provides expression vectors and host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with the expression of PRAT.

REFERENCES:
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Database Genbank, GenBank ACC. No.: H64488; Oct. 27, 1995, Hillier, L. et al.: "yu67a12.rl Homo sapiens cDNA clone 238846 5", XP002071139, WashU-Merck EST Project.
Hillier, et al., WashU-Merck EST Project, available Dec. 5, 1996, Genbank Accession No. AA146605.
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Szala, S. et al., "Molecular cloning of cDNA for the human tumor-associated antigen CO-029 and identification of related transmembrane antigens", Proc. Natl. Acad. Sci., 87: 6833-3837 (1990).

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