Human serpin

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C435S069200

Reexamination Certificate

active

07064182

ABSTRACT:
Members of the serine protease family play a role in carefully controlled processes, such as blood coagulation, fibrinolysis, complement activation, fertilization, and hormone production. The enzymatic activity of the serine proteases is regulated in part by serpins, serine protease inhibitors. Serpin dysfunction is associated with various disorders, including emphysema, blood clotting disorders, cirrhosis, Alzheimer disease, and Parkinson disease. Zserp11 is a new member of the serine protease inhibitor family.

REFERENCES:
patent: WO96/34957 (1996-11-01), None
patent: WO 96/34957 (1996-11-01), None
patent: WO96/40922 (1996-12-01), None
International Search Report for application No. PCT/US00/32100.

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