Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-12-16
2000-07-18
Martinell, James
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 696, 4352523, 435455, 536 235, C12N 1500
Patent
active
060905794
ABSTRACT:
SDR2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SDR2 polypeptides and polynucleotides in the design of protocols for the treatment of cancer, inflammation, autoimmunity, allergy, asthma, rheumatoid arthritis, CNS inflamation, cerebellar degeneration, Alzheimer's disease, Parkinsons disease, multiple sclerosis, amylotrophic lateral sclerosis, head injury damage, and other neurological abnormalities, septic shock, sepsis, stroke, osteoporosis, osteoarthritis, ischemia reperfusion injury, cardiovascular disease, kidney disease, liver disease, ischemic injury, myocardial infarction, hypotension, hypertension, AIDS, myelodysplastic syndromes and other hematologic abnormalities, aplastic anemia, male pattern baldness, and bacterial, fungal, protozoan and viral infections, among others, and diagnostic assays for such conditions.
REFERENCES:
Genbank Accession #N39774.
Genbank Accession #Z96934.
HGS Est #1688378.
George et al, in Macromolecular Sequencing and Synthesis Selected Methods and Applications, Schlesinger (ed.), Alan R. Liss, Inc., New York, NY, pp. 127-149., (1988).
Shirozu et al, Genomics 37: 273 (1996).
Albone Earl Francis
Kikly Kristine Kay
Han William T.
King William T.
Martinell James
SmithKline Beecham Corporation
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