Human heme-regulated initiation factor 2-alpha kinase

Details Human heme-regulated initiation factor 2-alpha kinase Human heme-regulated initiation factor 2-alpha kinase

2007-06-26

2007-06-26

Kemmerer, Elizabeth (Department: 1649)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C530S300000, C435S194000

Reexamination Certificate

active

11042643

ABSTRACT:
The present invention provides an isolated nucleic acid sequence encoding a human heme-regulated initiation factor 2 alpha kinase. In addition, the invention provides a method for inhibiting protein synthesis, inducing cellular differentiation, or inhibiting infection in human cells by administering an effective amount of a heme-regulated initiation factor 2 alpha kinase to the cells. Methods are also provided for modulating heme-regulated initiation factor 2 alpha kinase activity and determining the level of heme-regulated initiation factor 2 alpha kinase expression.

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