Human BNP-specific antibodies

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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5303871, 5303879, 5303881, 53038885, 5303882, 435326, 435336, 435344, 435346, C07K 1618, C07K 1622, C07K 1626

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active

061629022

ABSTRACT:
The present invention provides reagents and assays for the quantification of hBNP in biological fluid samples such as plasma or serum. Antibodies are provided which are monospecific to epitopes comprising the amino acid sequences 5-13, 1-10 and 15-25 of hBNP. These antibodies, and peptide fragments containing these sequences, can be employed in the assays of the invention, which may be carried out in a sandwich format or a competition format.

REFERENCES:
patent: 5114923 (1992-05-01), Seilhamer
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