Histamine antagonist triadiazole derivatives, compositions, and

Details Histamine antagonist triadiazole derivatives, compositions, and Histamine antagonist triadiazole derivatives, compositions, and

1986-02-04

1988-03-01

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514256, 514333, 514342, 544238, 544331, 544405, 546256, 546271, 546277, 546278, A61K 3138, A61K 31425, A61K 3144, A61K 31495

Patent

active

047286482

ABSTRACT:
New 3,4-diamino-1,2,5-thiadiazole oxide derivatives which are histamine H.sub.1 -antagonists. A specific compound of this invention is 3-[3-[N-(4-fluorobenzyl)-N-pyrid-2-yl-amino]propylamino]-4-[pyrimidin-4-yl -methylamino]-1,2,5-thiadiazole-1-oxide.

REFERENCES:
patent: 4374248 (1983-02-01), Crenshaw et al.
patent: 4394508 (1983-07-01), Crenshaw et al.
patent: 4532246 (1985-07-01), Ife
patent: 4532252 (1985-07-01), Sach

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