High-throughput transcriptome and functional validation...

Details High-throughput transcriptome and functional validation... High-throughput transcriptome and functional validation...

2005-08-02

2005-08-02

Fredman, Jeffrey (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S320100, C435S252800, C435S174000, C435S183000, C382S129000, C382S133000, C382S153000, C382S173000, C382S286000, C382S291000, C702S019000, C702S022000, C536S022100

Reexamination Certificate

active

06924109

ABSTRACT:
Methods for correlating genes and gene function are provided. Such methods generally involve selecting a candidate gene that appears to be correlated with a particular cellular state or activity and then validating the role of the candidate gene in establishment of such a cellular state or activity. Certain methods utilize RNA interference techniques in the validation process.

REFERENCES:
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patent: WO 00/44914 (2000-08-01), None
Paddison et al., Stable Suppression of Gene Expression by RNAI in Mammalian Cells, PNAS, (2002), vol. 99, No. 3, pp. 1443-1448.

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