Heterocyclic substituted pyridine or phenyl compounds with...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S358000, C544S359000

Reexamination Certificate

active

07417045

ABSTRACT:
The present application discloses a compound, or enantiomers, stereoisomers, rotamers, tautomers, racemates or prod rug of said compound, or pharmaceutically acceptable salts, solvates or esters of said compound, or of said prodrug, said compound having the general structure shown in Formula 1:or a pharmaceutically acceptable salt, solvate or ester thereof. Also disclosed is a method of treating chemokine mediated diseases, such as, palliative therapy, curative therapy, prophylactic therapy of certain diseases and conditions such as inflammatory diseases (non-limiting example(s) include, psoriasis), autoimmune diseases (non-limiting example(s) include, rheumatoid arthritis, multiple sclerosis), graft rejection (non-limiting example(s) include, allograft rejection, zenograft rejection), infectious diseases (e.g, tuberculoid leprosy), fixed drug eruptions, cutaneous delayed-type hypersensitivity responses, ophthalmic inflammation, type I diabetes, viral meningitis and tumors using a compound of Formula 1.

REFERENCES:
patent: 2006/0276480 (2006-12-01), Wong et al.
patent: WO 00/66558 (2000-11-01), None
patent: WO 2004/074287 (2004-09-01), None
patent: WO 2005/003127 (2005-01-01), None
West, Anthony R., Solid State Chemistry and Its Applications, Wiley, New York, 1988., p. 365.
International Search Report for International Application No. PCT/US2006/005128, mailed Jun. 22, 2006 (4pgs.).

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