Heterocyclic inhibitors of MEK and methods of use thereof

Details Heterocyclic inhibitors of MEK and methods of use thereof Heterocyclic inhibitors of MEK and methods of use thereof

2004-11-18

2009-10-06

Wilson, James O (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S300000

Reexamination Certificate

active

07598383

ABSTRACT:
Disclosed are compounds of the Formula Iand pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8and R9, W, X and Y are as defined in the specifications. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.

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