Heterocyclic compounds having anti-diabetic activity and their u

Details Heterocyclic compounds having anti-diabetic activity and their u Heterocyclic compounds having anti-diabetic activity and their u

1999-03-03

2000-09-12

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514414, 548132, 548465, 548467, A61K 3142, A61K 3140, C07D41312, C07D20914

Patent

active

061178934

ABSTRACT:
Compound of formula (I): ##STR1## [wherein: X represents an unsubstituted or substituted indolyl, indolinyl, azaindolyl, azaindolinyl, imidazopyridyl or imidazopyrimidinyl group; Y represents an oxygen or sulphur atom; Z represents a 2,4-dioxothiazolidin-5-ylidenylmethyl, 2,4-dioxothiazolidin-5-ylmethyl, 2,4-dioxooxazolidin-5-ylmethyl, 3,5-dioxooxadiazolidin-2-ylmethyl or N-hydroxyureidomethyl group; R represents a hydrogen atom, an alkyl group, an alkoxy group, a halogen atom, a hydroxy group, a nitro group, an aralkyl group or a unsubstituted or substituted amino group; and m is an integer of from 1 to 5] have hypoglycemic and anti-diabetic activities.

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The Ring Index--2nd Edition, Austin Patterson et al (America Chemical Society), p. 157 (1960).

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