Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-05-15
1999-06-29
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546164, 546141, 546146, 546153, 514307, A61K 3147, C07D21504
Patent
active
059169010
ABSTRACT:
The present invention relates to novel N-substituted amino alcohols, amino acids and acid derivatives thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
REFERENCES:
patent: 4965259 (1990-10-01), Rozsa et al.
Kalman, A., et al. Acta Biochim. Biophys. Hung., vol. 24, Nos. 1-2, pp. 143-158 (1989).
Andersen Knud Erik
Hohlweg Rolf
J.o slashed.rgensen Tine Krogh
Konigova Otylie
Kovandova Martina
Aulakh Charanjit S.
Lambris Elias J.
Novo Nordisk A S
Rotman Alan L.
Rozek Carol E.
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