Heterocyclic aminomethyl compounds

Details Heterocyclic aminomethyl compounds Heterocyclic aminomethyl compounds

1997-11-07

1999-07-06

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544 52, 544105, 544364, 544368, 544295, 546187, 546201, 5142242, 5142305, 514316, 514323, 514256, A61K41310, A61K41710, C07D 31495, C07D 31535

Patent

active

059197846

ABSTRACT:
A compound of general formula (I): ##STR1## where A, X, R.sub.1, Y, n and Ar are defined in the description. Medicinal products containing the same are useful as D.sub.4 receptor Ligands.

REFERENCES:
patent: 4960778 (1990-10-01), Lesieur et al.
patent: 5234924 (1993-08-01), Taverne et al.
Society of Biological Psychiatry, 1997, 42 8, 648.
Meador-Woodruff et al., "Dopamine Receptor Transcript Expression . . . ", Arch. Gen. Psyciatry, 1997, 54, 12, 1089.
Rubenstein et al., "Mice Lacking Dopamine D4 Receptors . . . ", Cell., 1997, 90, 6.
Reynolds, "The Importance of Dopamine D4 Receptors in the Action and Development of Antipsychotic Agents," Drugs, vol. 51, No. 1, pp. 7-11, 1996.
Kulagowski et al., "Dopamine D4 Receptor Antagonists," Current Pharmaceutical Design, vol. 3, pp. 355-366, 1997.
Manki et al., "Dopamine D2, D3 and D4 Receptor and Transporter Gene Polymorphisms and Mood Disorders," Journal of Affective Disorders, vol. 40, pp. 7-13, 1996.

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