Heteroaryl substituted pyrazole modulators of metabotropic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S406000, C546S275400, C548S364100

Reexamination Certificate

active

07569592

ABSTRACT:
Pyrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorder and panic, as well as in the treatment of pain, circadian rhythm disorders, and other diseases.

REFERENCES:
patent: 2833779 (1958-05-01), Fields et al.
patent: 6660753 (2003-12-01), Van Wagenen et al.
patent: 7087601 (2006-08-01), Arruda et al.
patent: 7105548 (2006-09-01), Cosford et al.
patent: 7112595 (2006-09-01), Wagenen et al.
patent: 7253190 (2007-08-01), Cosford et al.
patent: 7268151 (2007-09-01), Cosford et al.
patent: 2005/0085514 (2005-04-01), Cosford et al.
patent: 2005/0153986 (2005-07-01), Chen et al.
patent: 2006/0189661 (2006-08-01), Wagenen et al.
patent: 2006/0193926 (2006-08-01), Cosford et al.
patent: 2006/0194807 (2006-08-01), Cosford et al.
patent: 2006/0217420 (2006-09-01), Cosford et al.
patent: 2007/0027321 (2007-02-01), Kamenecka et al.
patent: 2007/0149547 (2007-06-01), Bonnefous et al.
Passarotti et al. “Antiinflammatory activity of some 4-substituted-5-amminopyrazole derivatives” Currents in Toxicology and Therapy, 1993, vol. 1, No. 2, pp. 89-93.
M. A. Halcrow et al., “Syntheses, Structures and Electrochemistry of [CuL1(Lr)]BF4[LI=3- {2,3-Dimethoxyphenyl)-1-(2-pyridyl)Pyrazole; Lr=tris(3-arylpyrazolyl)-hydroborate] and [CuL1 2][BF4]2. Effects of graphitic Interactions on the Stability of an Aryl Radical Cation”, J. Chem. Soc., Dalton Trans, 1997, vol. 21, pp. 4025-4035.
G. I. Denis et al., “Synthesis and Some Transformations of N-)Beta-Acylethyl) Aminopyridines and N-(Beta-Acylethyl) Aminoquinolines”, Zhurnal Organicheskol Khimii, 1977, vol. 13, No. 1, pp. 199-204, Translated in V. Kapsukas Vil'nyus State University.
Database Caplus, Accession No. 1964:45681, Kost et al., Reactions of Hydrazine Derivatives. Zh. Obshch. Khim. 1963, vol. 33, No. 11, 3603-3613 (English abstract).

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