Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-03-18
2008-03-18
Coleman, Brenda L. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S278000, C435S810000, C514S283000, C514S090000, C514S274000, C514S186000, C514S252160, C514S252180, C514S475000, C424S144100, C424S142100, C424S649000, C424S770000
Reexamination Certificate
active
10850429
ABSTRACT:
Heteroaryl-fused pyrimidinyl compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the heteroaryl-fused pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the heteroaryl-fused pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.
REFERENCES:
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Coleman, P.J.; Fraley, M. E.; Expert. Opin. Ther. Patents; 2004; 14(12); 1659-1667.
Yan et al, “Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences”J. Mol. Biol. 335:547-554, 2004.
Burger Matthew T.
Constantine Ryan N.
Lagniton Liana Marie
Wang Weibo
Abrahamson Susan L.
Chiron Corporation
Coleman Brenda L.
Harbin Alisa A.
Moore Susanna
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