Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-06-05
1999-02-23
Woodward, Michael P.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 2432, 536 243, 435 5, 435 693, 435 912, 435 9133, C07H 2104, C07H 2102, C12Q 170
Patent
active
058745637
ABSTRACT:
Polypeptide antigens are disclosed which are immunoreactive with sera from individuals having a non-A, non-B, non-C, non-D, non-E Hepatitis, herein designated Hepatitis G Virus (HGV). Corresponding genomic-fragment clones containing polynucleotides encoding the open reading frame sequences for the antigenic polypeptides are taught. The antigens are useful in diagnostic methods for detecting the presence of HGV in test subjects. The antigens are also useful in vaccine and antibody preparations. In addition, the entire coding sequences of two HGV isolates are disclosed. Methods are presented for nucleic acid-based detection of HGV in samples and also methods for the isolation of further genomic sequences corresponding to HGV.
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Fry Kirk E.
Kim Jungsuh P.
Linnen Jeffrey M.
Wages John
Young LaVonne Marie
Brumback Brenda G.
Dehlinger Peter J.
Evans Susan T.
Fabian Gary R.
Genelabs Technologies, Inc.
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