Hepatitis B virus vectors for gene therapy

Chemistry: molecular biology and microbiology – Vector – per se

Reexamination Certificate

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C435S069100, C536S024100, C514S04400A

Reexamination Certificate

active

07001760

ABSTRACT:
The present invention relates to novel hepatitis B virus vectors for use in gene therapy which can deliver therapeutic genes to liver cells. The invention also provides methods for the production of novel recombinant hepatitis B viruses. The recombinant viruses produced by this invention can deliver therapeutic genes specifically to liver cells either through in vivo or ex vivo therapy protocols. This vector can be used not only to treat liver diseases but also genetic diseases.

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