Hairpin ribozymes

Details Hairpin ribozymes Hairpin ribozymes

1994-10-11

1997-05-20

Elliott, George C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

4353201, 435325, 435354, C12N 510, C12N 1563, C07H 2104

Patent

active

056313594

ABSTRACT:
Hairpin ribozyme lacking a substrate moiety, comprising at least six bases in helix 2 and able to base-pair with a separate substrate RNA, wherein the ribozyme comprises one or more bases 3' of helix 3 able to base-pair with the substrate RNA to form a helix 5 and wherein the said ribozyme can cleave and/or ligate the separate RNA(s) in trans.

REFERENCES:
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