Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1990-03-16
1991-12-24
Dees, Jose G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514540, 514634, 546220, 548473, 548478, 548547, 560 34, 564104, 568 77, A01N 3712, A01N 3124
Patent
active
050753355
ABSTRACT:
A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: ##STR2## in which Y is a group of the formula: --(CH.sub.2).sub.m --, m being an integer of 2 or 3, ##STR3## or a group of the formula:
REFERENCES:
Choay et al., Chemical Abstracts, vol. 95, 1981 p. 639, :132533x.
Hishinuma Ieharu
Kawashima Hidetoshi
Kawata Tsutomu
Miyamoto Kaname
Miyazawa Shuhei
Carr Deborah D.
Dees Jos,e G.
Eisai Co. Ltd.
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