Guanidinobenzoic ester derivative

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514328, 514376, 514410, 514417, 546220, 548227, 548424, 548479, 548547, 560 34, 562439, A61K 3140, C07D207404

Patent

active

048016039

ABSTRACT:
A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: ##STR2## in which Y is a group of the formula: --(CH.sub.2).sub.m --, m being an integer of 2 or 3, ##STR3## or a group of the formula:

REFERENCES:
patent: 3894043 (1975-07-01), Moser
patent: 4021472 (1977-05-01), Fujii
patent: 4224342 (1980-04-01), Fujii
patent: 4283418 (1981-08-01), Fujii

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