Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-06-15
1995-02-28
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514183, 514211, 514212, 514220, 5142355, 514307, 514312, 514314, 514316, 514319, 514321, 514331, 514822, 540481, 540506, 540544, 540573, 540597, 544130, 544162, 544168, A61K 31445, C07D21122, C07D21126, C07D40112
Patent
active
053937600
ABSTRACT:
Compounds of the formula ##STR1## wherein L, M, R, T and X are set forth in the description, as well as hydrates or solvates thereof, which inhibit thrombin-induced platelet aggregation and clotting of fibrinogen in plasma, are described. The compounds of formula I are prepared by amidination or, depending on whether L is NH or O, by amide formation or esterification.
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Ackermann Jean
Banner David
Gubernator Klaus
Hadvary Paul
Hilpert Kurt
Datlow Philip I.
Epstein William H.
Gould George M.
Hoffmann-La Roche Inc.
Picut Catherine A.
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