Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Reexamination Certificate
2006-07-04
2006-07-04
Monshipouri, Maryam (Department: 1653)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
C530S350000, C435S320100, C435S252300, C435S006120
Reexamination Certificate
active
07070971
ABSTRACT:
Novel glycosylsulfotransferases (GST-4α, GST-4β, and GST-6) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including various diagnostic and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of at least one of GST-4α, GST-4β, and GST-6.
REFERENCES:
patent: 5776772 (1998-07-01), Paulson et al.
patent: 6054304 (2000-04-01), Taniguchi et al.
patent: 6265192 (2001-07-01), Bistrup et al.
patent: 6365365 (2002-04-01), Bistrup et al.
patent: 6558935 (2003-05-01), Tang et al.
patent: 821 066 (1997-07-01), None
patent: WO 9919339 (1999-04-01), None
patent: WO 01/79468 (2001-10-01), None
Lee et al., BBRC, 263(2), 543-549, 1999.
GenBank accession No. AA 261202, Mar. 18, 1997.
GenBank accession No. AI 282873, Nov. 23, 1998.
GenBank accession No. AC 009105, Apr. 25, 2001.
GenBank accession No. AC 009163, Aug. 29, 2003.
GenBank accession No. AC 011934, Mar. 12, 2000.
GenBank accession No. AF 176838, Sep. 22, 1999.
GenBank accession No. AC 026419, May 12, 2002.
GenBank accession No. AI 528511, Mar. 17, 1999.
GenBank accession No. AC 010547, Sep. 29, 2001.
GenBank accession No. AC 025287, Jan. 26, 2002.
Lee et al., “Mus musculus intestine N-acetylgluco samine 6-0 sulfotransferase (I-GIcNAc-6-ST) gene, complete cds.” Sep. 23, 1999 Database accession No. AF176841.
Lee et al., “Mus musculus intestine N-acetylglucosamine 6-0 sulfotransferase (I-GIcNAc-6-ST) gene, complete cds,” Sep. 23, 1999 Database accession No. AF176840.
Fukuta, et al. “Molecular Cloning and Characterization of Human Keratan Sulfate Gal-6-Sulfotransferase,”J. Biol. Chem.(Dec. 19, 1997) 272:32321-32328.
Habuchi, et al. “Enzymatic Sulfation of Galactse Residue of Keratan Sulfate by Chondroitin 6-Sulfate by Chondroitin 6-Sulfate by Chondroitin 6-Sulfotransferase,”Glycobiology(Jan. 1996) 6:51-57.
Fukuta, et al. Molecular Cloning and Expression of Chick Chondrocyte Chondroitin 6-Sulfotransferase,:J. Biol. Chem.(1995) 270:185775-18580.
Habuchi, et al. “Purification of Chondroitin 6-Sulfotransferase Secreted from Cultured Chick Embryo Chondrocytes,”J. Biol. Chem.(1993) 268:21968-21974.
Lee et al., “Mus musculus intestine N-acetylgluco samine 6-0 sulfotransferace (I-GIcNAc-6-ST) gene, complete cds.” Sep. 23, 1999 Database accession No. AF17681.
Lee et al., “Mus musculus intestine N-acetylglucosamine 6-0 sulfotransferase (I-GIcNAc-6-ST) gene, complete cds.” Sep. 23, 1999 Database accession No. AF176480.
Lee et al., “Mus musculus intestine N-acetylglucosamine 6-0 sulfotransferase (I-GIcNAc-6-ST) gene, complete cds.” Sep. 23, 1999 Database accession No. AF176839.
Lee et al., “Homo sapiensintestine N-acetylglucosamine-6-0-sulfotransferase, complete cds” Sep. 23, 1999 Database accession No. AF176838.
Doe Joint Genome Inst.: “Homo sapienschromosome 16 clone RP11-455E15, Working Draft Sequence, 17 unordered pieces” Aug. 4, 1999, Database accession No. AC009105.
NCI GCAP: “wj46c01.xl NCI—CGAP—lu19Homo sapienscDNA clone IMAGE: 2405856” Jul. 13, 1999, Database accession No. AI824100.
Birren et al., “Homo sapienschromosome 18, clone RP11-29013, complete sequence” Feb. 7, 2000, Database accession No. AC022662.
Hillier et al. “zu27h10.rl Soares ovary tumor NbHOTHomo sapienscDNA clone IMAGE: 739267” May 19, 1997, Database Accession No. AA421254.
Zhao et al. “-11-252I7.TV RPCI-11Homo sapiensgenomic clone” Apr. 27, 1999 Database Accession No. AQ481324.
Zhao et al. “CITBI-E1-2563I17.TF CITBI-EIHomo sapiensgenomic clone” Mar. 25, 1999 Database accession No. AQ424845.
Nakao et al.,Homo sapienssquamous cell carcinoma antigen recognized by T cell (SART-2) mRNA, complete cds.: Oct. 6, 1999 Database accession No. AF098066.
Human Genome Sci Inc. “Human secreted protein encoded by gene 5 clone HSABG21” Aug. 17, 1999 Database accession No. AAX79015.
Human Genome Sci Inc.: “Human secreted protein encoded by gene 4 clone HSABG21” Aug. 17, 1999 Database accession No. AAY14415.
Arakawa et al., “Mus musculus adult male diencephalons cDNA, Riken full-length enriched library, clone: 9330132E09, 3′ end partial sequence” Jun. 14, 2000 Database accession No. BB077136.
Marra et al., ui33cll.yl Soares mouse urogenital ridge NMURMus musculus cDNA clone IMAGE: 1853108 5′, mRNA sequence Mar. 24, 19999 Database accession No. AI528511.
Marra et al., ui43b06.xl Sugano mouse embryo mewa Mus musculus cDNA clone IMAGE: 1885139 3′, mRNA sequence Oct. 8, 1998 Database accession No. AI173964.
Hemmerich Stefan
Lee Jin Kyu
Rosen Steven
Borden Paula A.
Bozicevic Field & Francis LLP
Field Bret E.
Monshipouri Maryam
Syntex (U.S.A.) LLC
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