Glycoprotein IIb/IIIa antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514456, 546196, 549398, 549404, 549407, C07D31102, A61K 3135, A61K 31335

Patent

active

057313245

ABSTRACT:
This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, benzopyran, isoquinoline, isoquinolone, tetrahydronaphthalene, dihydronaphthalene, or tetralone, substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.

REFERENCES:
Ellis, G.P., et al., Journal of Medicinal Chemistry, 1978, vol. 21, No. 11, "Benzopyrones. 14. Synthesis and Antiallergic Properties of Some N-Tetrazolylcarbosamides And Related Compounds".

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