Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1978-11-01
1983-07-26
Hazel, Blondel
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, 424 88, A61K 3702, C07C10352, C07G 700
Patent
active
043953999
ABSTRACT:
Glycopeptides according to the present invention have the formula: ##STR1## wherein n=1 or 2; R is a residue of an aminoacid or linear peptides built of 2 to 5 amino acid residues.
These compounds are prepared by the method involving condensation of unblocked muramyl-containing N-acetylamino-sugars of the formula: ##STR2## wherein n=1 or 2, with blocked aminoacids or peptides. The method of this invention makes it possible to produce synthetic glycopeptides manifesting a biological activity. These compounds possess an antitumor and adjuvant activity.
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Andronova Tatyana M.
Ivanov Vadim T.
Malkova Veronika P.
Ovchinnikov Jury A.
Rostovtseva Larisa I.
Hazel Blondel
Institut Bioorganicheskoi Khimii Imeni M.M. Shemyakina Akademii
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