Glycohemoglobin determination

Details Glycohemoglobin determination Glycohemoglobin determination

1981-07-31

1983-02-08

Marantz, Sidney

Chemistry: analytical and immunological testing

Hemoglobin, myoglobin, or occult blood

Glycosylated hemoglobin

2524081, G01N 3372, G01N 3366, G01N 3352

Patent

active

043727476

ABSTRACT:
A method of measuring glycosylated hemoglobin featuring, in one aspect, providing a sample containing hemoglobin, including an unknown amount of glycosylated hemoglobin, contacting the sample with an oxidizing agent to generate formaldehyde, and measuring the formaldehyde as a measure of glycosylated hemoglobin, the measuring being carried out by reacting the formaldehyde with a water-soluble amine or an ammonium salt and a .beta.-diketone to generate a fluorescent compound whose fluorescence is measured as a measure of glycosylated hemoglobin.

REFERENCES:
patent: 4268270 (1981-05-01), Gabbay
Belman (1963) Analytica Chimica Acta 29, 120.varies.126.
Rahbar (1968) Clin. Chim. Acta 22, 296-298.
Trivelli et al. (1971) N. Eng. J. Med. 284, 353-357.
Gabbay et al. (1977) J. Clin. Endocrin, Metab. 44, 859-864.
Fluckiger et al. (1976) FEBS Lett. 71, 356-360.
Massamiri et al. (1978) Anal. Bioch. 91, 618-625.
Gabbay et al. (1978) American Society for Clinical Investigation, San Francisco, Cal.
Bunn et al. (1978) American Society of Biological Chemists.
Bunn et al. (1976) J. Clin. Invest. 57, 1652-1659.
Bunn et al. (1975) Biochem. Biophys. Res. Comm. 67, 103-109.
Bunn et al. (1978) Science 250, 21-27.

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