Glucose isomerization with iron ion-thiol activator ion-glucose

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195114, C12D 1302

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active

041135652

ABSTRACT:
Iron ions may be effectively used as a metal activator or co-metal activator in glucose isomerization when used in conjunction with thiol activators. The thiol activators are characterized as being able to cleave disulfide linkages and include reducing reagents such as water-soluble SO.sub.3.sup.= producing metal salts, ascorbic acid, thiocyanates, thioglycollates, etc. The thiol activator-iron ion activating system is especially effective when used in conjunction with at least one other metal ion activator such as magnesium, manganese or cobalt ions. Effective enzymatic glucose isomerization, without using cobalt ions, is achievable by a magnesium-iron-thiol activator-isomerase system.

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Tz-Yuan et al., "D-Xylose Isomerase of Streptomyces griseus," Acta Biochimica et Biophysica Sinca", vol. 14, No. 3, pp. 342-350 (1964).
Perry et al., Chemical Engineer's Handbook, 4th ed., McGraw-Hill Book Co., New York, (1963) pp. 23-27.

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