Glucopyranosyloxy-substituted aromatic compounds,...

Details Glucopyranosyloxy-substituted aromatic compounds,... Glucopyranosyloxy-substituted aromatic compounds,...

2008-05-13

2008-05-13

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S004100

Reexamination Certificate

active

07371732

ABSTRACT:
The present invention relates to glucopyranosyloxy-substituted aromatic groups of general formulawhereinR1to R6and R7a, R7b, R7care defined as in claim 1, the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological properties, particularly an inhibitory effect on the sodium-dependent glucose cotransporter SGLT2, the use thereof for the treatment of diseases, particularly metabolic disorders such as diabetes, and the preparation thereof.

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patent: 6627611 (2003-09-01), Tomiyama et al.
patent: 2005/0059614 (2005-03-01), Fujikura et al.
patent: 2005/0080022 (2005-04-01), Fujikura et al.
patent: 2005/0113315 (2005-05-01), Fujikura et al.
patent: WO 01/74834 (2001-10-01), None
Adachi et al., “T-1095, a Renal Na+-Glucose Transporter Inhibitor, Improves Hyperglycemia in Streptozotocin-Induced Diabetic Rats” Metabolism (2000) vol. 49, No. 8, pp. 990-995.

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