Glucopyranose derivatives

Details Glucopyranose derivatives Glucopyranose derivatives

1993-05-20

1999-11-09

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 172, 536 175, 536 54, 536118, 536122, 514885, A61K 3100, C07H 1300, C07H 1100, C07D30900

Patent

active

RE0363855

ABSTRACT:
This invention relates to glucopyranose compounds of formula (I) and (IA) ##STR1## and the non-toxic salts thereof wherein the substituents are as defined herein. Such materials possess enhancing activity of cellular immunity (e.g. mitogenic activity) to living tissue and therefore are useful as anti-tumor agents.

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patent: 4399126 (1983-08-01), Schaub et al.
patent: 4536572 (1985-08-01), Kim et al.
Agricultural and Biological Chemistry, vol. 48, No. 1, Jan. 1984, pp. 251-252.
"Synthesis of biologically active, novel monosaccharide analogs of lipid A".
Chemical & Pharmaceutical Bulletin, vol. 33, No. 10, Oct. 1985, pp. 4621-4624.
"Antitumor activity and biological effects of chemically synthesized etc".
Sobel et al., "Steryl Sulfates. II. Isolation and Separation of Sterols," J. Am. Chem. Soc., 64, 361 (1942).
Tetrahedron Letters, vol. 26, No. 12, pp. 1545-1548, 1985, Great Britain.

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