Genotyping method using DNA chip

Details Genotyping method using DNA chip Genotyping method using DNA chip

2004-01-23

2008-03-18

Smith, Carolyn L. (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C435S006120, C702S023000, C703S002000, C706S013000

Reexamination Certificate

active

07346458

ABSTRACT:
A robust genotyping method using a DNA chip is provided. In the DNA chip used in the genotyping method, optimal probe pairs of a wild-perfect match probe and a mutant-perfect match probe are immobilized for each mutation site on a substrate. The method includes setting up a genotyping algorithm using data obtained from hybridization of an identified standard nucleic acid to the DNA chip, and genotyping an unknown target nucleic acid by substituting input vectors that are calculated from hybridization of the target nucleic acid to the DNA chip into the genotyping algorithm. The results of genotyping the target nucleic acid using the optimal probe pairs for each mutation site are statistically robust to errors.

REFERENCES:
patent: 6027880 (2000-02-01), Cronin et al.
patent: 6300063 (2001-10-01), Lipshutz et al.
patent: 6303301 (2001-10-01), Mack
patent: 2003-0020232 (2003-03-01), None
patent: 2003-0072709 (2003-09-01), None
Office Action of Korean Patent Office regarding corresponding Korean Patent Application No. 10-2003-0005025, dated Dec. 23, 2004.
“Applied Logistic Regression”; Second Edition; Authors: David W. Hosmer and Stanley Lemeshow; Wiley Series in Probability and Statistics; pp. 1-30, 2000.

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