Gastric acid secretion inhibiting N-(imidazol-1-ylalkyl)thiourea

Details Gastric acid secretion inhibiting N-(imidazol-1-ylalkyl)thiourea Gastric acid secretion inhibiting N-(imidazol-1-ylalkyl)thiourea

1983-04-07

1985-04-30

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548336, A61K 31415, C07D23361

Patent

active

045144133

ABSTRACT:
N-substituted imidazole derivatives of the formula I ##STR1## where R.sup.1, R.sup.2 and R.sup.3 are identical or different and are each hydrogen or alkyl with 1 or 3 carbon atoms and Alk is an alkylene chain of 2 to 4 carbon atoms, and their salts with physiologically tolerated acids, processes for their preparation, drugs containing a compound of the formula I or one of its salts, and their use for treating disorders associated with gastric hyperacidity.

REFERENCES:
patent: 3876647 (1975-04-01), Durant et al.
patent: 3897444 (1975-07-01), Durant et al.
patent: 3975530 (1976-08-01), Durant et al.
patent: 3978075 (1976-08-01), Toth et al.
patent: 4226874 (1980-10-01), Durant et al.
patent: 4233302 (1980-11-01), Martin-Smith
patent: 4279911 (1981-07-01), Martin-Smith
patent: 4304780 (1981-12-01), Martin-Smith
patent: 4386211 (1983-05-01), Henderson
R. N. Brogden et al., Drugs 24 (1982), 267-303.
G. J. Durant et al., J. Med. Chem. 20 (1977), 901.

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