Fusion protein between human macif and a heterologous pi anchor

Details Fusion protein between human macif and a heterologous pi anchor Fusion protein between human macif and a heterologous pi anchor

1994-08-17

1996-07-02

Draper, Garnette D.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530324, 530380, 435 697, C07K 1447, C07K 1900

Patent

active

055323391

ABSTRACT:
Fusion proteins comprising the extracellular domain of the human MACIF (Membrane Attack Complex Inhibition Factor) gene product and a heterologous phosphatidylinositol (PI) anchor domain are provided.

REFERENCES:
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Kieffer, B., et al., Biochem. 33:4471-4482, 1994.
Ferguson, M. A. J., et al. Ann. Rev. Biochem. 57:285-320, 1988.
Journal of Biochemistry, vol. 104, No. 4, Oct. 1988 pp. 633-637, Y. Sugita et al.
Okada et al. "20 kDa Homologous Restriction Factor . . . " BBRC v. 162(3) pp. 1553-1559 Aug. 15, 1989.
Davies et al. "CD59, An LY-6-Like Protein . . . " J. Exp. Med. vol. 170, pp. 637-654. Sep. 1, 1989.
Stefanova et al "Characterization of a Broadly Expressed Human Leukocytc Surface Antigen . . . " Mol. Imm. v. 26(2) pp. 153-161 Feb. 1989.
Seed et al. "Molecular Cloning of the CD2 Antigen . . . " Proc. Natl. Acad. Sci. USA vol. 84 pp. 3365-3369 (May 1987).

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