Fused purine derivatives

Details Fused purine derivatives Fused purine derivatives

2006-02-28

2006-02-28

Berch, Mark L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S220000, C514S267000, C514S233200, C540S471000, C540S559000, C544S251000, C544S115000, C544S118000, C544S271000, C544S272000, C544S276000

Reexamination Certificate

active

07005430

ABSTRACT:
A condensed purine derivative represented by Formula (I):wherein X—Y-Z represents R1N—C═O or N═C—W, R2represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted aromatic heterocyclic group, a substituted or unsubstituted alicyclic heterocyclic group or the like, n represents an integer of from 0 to 3, V1represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aromatic heterocyclic group, V2represents a substituted lower alkyl group or a substituted or unsubstituted aromatic heterocyclic group, and when V1represents a hydrogen atom, a lower alkyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted aryl group, and for example, X—Y-Z represents R1aN—C═O and R2represents a substituted lower alkyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted alicyclic heterocyclic group, a halogen atom, a lower alkylthio group, —NR7R8, —CO2H, a lower alkoxycarbonyl group, —COHal, —CONR9R10or —CHO, V2may represent a lower alkyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted aryl group; or a pharmacologically acceptable salt thereof.

REFERENCES:
patent: 4338319 (1982-07-01), Kjellin et al.
patent: 5064947 (1991-11-01), Peet et al.
patent: 5086176 (1992-02-01), Peet et al.
patent: 5270316 (1993-12-01), Suzuki et al.
patent: 5719279 (1998-02-01), Küfner-Mühl et al.
patent: 6306847 (2001-10-01), Tsumuki et al.
patent: 6339072 (2002-01-01), Martin et al.
patent: 6489331 (2002-12-01), Shimada et al.
patent: 6605601 (2003-08-01), Lin et al.
patent: 256692 (1988-02-01), None
patent: 386683 (1990-09-01), None
patent: 380111 (1990-10-01), None
patent: 0390111 (1990-10-01), None
patent: 747356 (1996-12-01), None
patent: 884318 (1998-12-01), None
patent: 1092435 (2001-04-01), None
patent: 10158267 (1998-06-01), None
patent: 9815555 (1998-04-01), None
patent: 0001388 (2000-01-01), None
35 J. Med. Chem. 3578-3581 (1992).
36 J. Med. Chem. 2508-2518 (1993).
23 J. Med. Chem. 1188-1198 (1980).
40 J. Med. Chem. 3248-3253 (1997).
30 J. Heterocycl. Chem. 241-246 (1993).
J. Chem. Soc. Perkin I 739-743 (1973).
41 Bull. Chem. Soc. Japan 1634-1638 (1968).
29 J. Org. Chem. 2658-2663 (1964).
Synthesis 1144-1151 (1992).
2 J. Heterocycl. Chem. 1 (1965).
23 J. Org. Chem. 575-581 (1958).
44 Tetrahedron 5525-5540 (1988).
64 J. Org. Chem. 6411-6417 (1999).
43 J. Org. Chem. 2539-2541 (1978).
38 Tetrahedron 3597-3604 (1982).
16 (35) J. Med. Chem. 3066-3075 (1992).
32 (6) J. Med Chem. 1231-1237 (1989).
127 Endocrinology 126-31 (1990).
5 Pharmacotherapy 43-62 (1985).
7 Pharmacology and Clinic 121-129 (1997).
English Language Abstract for JP Appln. No. 10-158267.

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