Fused bicyclic mTor inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S262100, C514S243000, C544S184000

Reexamination Certificate

active

07923555

ABSTRACT:
Compounds represented by Formula (I)or a pharmaceutically acceptable salt thereof, are inhibitors of mTOR and useful in the treatment of cancer.

REFERENCES:
patent: 5869485 (1999-02-01), Missbach
patent: 6001839 (1999-12-01), Calderwood et al.
patent: 7651687 (2010-01-01), Buck et al.
patent: 2002/0156081 (2002-10-01), Hirst et al.
patent: 2003/0073218 (2003-04-01), Shokat
patent: 2003/0187001 (2003-10-01), Calderwood et al.
patent: 2005/0004142 (2005-01-01), Adams et al.
patent: 2005/0130994 (2005-06-01), Chen et al.
patent: 2006/0019957 (2006-01-01), Crew et al.
patent: 2006/0084654 (2006-04-01), Beck et al.
patent: 2006/0235031 (2006-10-01), Arnold et al.
patent: 2007/0112005 (2007-05-01), Chen et al.
patent: 2007/0149521 (2007-06-01), Crew et al.
patent: 2007/0167383 (2007-07-01), Roberts et al.
patent: 2007/0203143 (2007-08-01), Sheppard et al.
patent: 2007/0280928 (2007-12-01), Buck et al.
patent: 2007/0293516 (2007-12-01), Knight et al.
patent: 2008/0032960 (2008-02-01), Knight et al.
patent: 2009/0099174 (2009-04-01), Smith
patent: 2009/0124638 (2009-05-01), Shokat et al.
patent: 2005097800 (2005-10-01), None
patent: 2006068760 (2006-06-01), None
patent: 2007115620 (2007-10-01), None
patent: 2007126841 (2007-11-01), None
Kinkade, C.W. et al. (2008) Journal of Clinical Investigation 118(9):3051-3064.
Legrier, M. et al. (2007) Cancer Research 67(23):11300-11308.
Papadimitrakopoulou, V. and Adjei, A.A. (2006) Journal of Thoracic Oncology 1(7): 749-751.
Bergstrom, D. et al. (1981) Journal of Organic Chemistry 46(7):1423-1431.
Bergstrom, D. et al. (1991) Journal of Organic Chemistry 56(19):5598-5602.
Bishop, A. et al. (1999) Journal of the American Chemical Society 121(4):627631.
Buzko, O. et al. (2002) Journal of Computer-Aided Design 16(2):113-127.
Hubbard, R.D. et al. (2007) Bioorganic & Medicinal Chemistry Letters 17(19):5406-5409.
International Preliminary Report on Patentability in PCT/US2006/044461 May 20, 2008.
International Search Report in PCT/US2006/044461 May 20, 2008.
Prousek, J. (1984) Collection of Czechoslovak Chemical Communications 49(8):1788-1794.
Raslan, M.A. et al. (2000) Heteroatom Chemistry 11(2):94-201.
Seela, F. et al. (2000) Helvetica Chimica Acta 83(5):910-927.
Schram, K. et al. (1974) Journal of Carbohydrates, Nucleosides, Nucleotides 1(1):39-54.
Written Opinion of the International Search Authority in PCT/US2006/044461 May 20, 2008.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Fused bicyclic mTor inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fused bicyclic mTor inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fused bicyclic mTor inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2665576

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.