Fused bicyclic amide compounds and medicinal use thereof

Details Fused bicyclic amide compounds and medicinal use thereof Fused bicyclic amide compounds and medicinal use thereof

2006-09-26

2006-09-26

Shameem, Golam M. M. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S315000, C514S323000, C546S184000, C546S192000, C546S196000, C546S200000, C546S202000, C544S106000, C544S111000, C544S358000

Reexamination Certificate

active

07112594

ABSTRACT:
Compounds represented by the following general formula (I) wherein ring A is benzene, cyclohexane, pyridine, piperidine, a derivative thereof, imidazole, a derivative thereof, etc.; the ring B represents benzene, cyclohexane, pyrrole or a derivative thereof, furan, thiophene, etc.; R1, R2and R3represent each hydrogen, alkyl, halogen, hydroxyl, alkoxy, etc.; W represents hydrogen, alkyl or hydroxycarbonylalkyl; X represents halogen, cyano, nitro, etc.; X′ represents hydrogen, halogen, etc.; and Y represents alkyl, hydroxyalkyl, hydroxycarbonylalkyl, aminoalkyl, etc.; salt thereof, and drugs comprising these compounds. Because of having an exellent effect of inhibiting activated lymphocyte proliferation, these compounds are usefull as preventives or remedies for various autoimmune diseases.

REFERENCES:
patent: 3413308 (1968-11-01), Bockstahlev
patent: 3479348 (1969-11-01), Yamamoto et al.
patent: 4145364 (1979-03-01), Mulvey et al.
patent: 4179578 (1979-12-01), Fleck et al.
patent: 4800211 (1989-01-01), Tischler et al.
patent: 6015829 (2000-01-01), Ishibuchi et al.
patent: 6069151 (2000-05-01), Dyke et al.
patent: 6166028 (2000-12-01), Bloom et al.
patent: 6207693 (2001-03-01), Setoi et al.
patent: 6262082 (2001-07-01), Bloom et al.
patent: 6555561 (2003-04-01), Bloom et al.
patent: 6716987 (2004-04-01), Ohshima et al.
patent: 2441959 (1975-03-01), None
patent: 2892 (1979-07-01), None
patent: 23569 (1981-02-01), None
patent: 29992 (1981-06-01), None
patent: 594019 (1994-04-01), None
patent: 0 625 522 (1994-11-01), None
patent: 628038 (1994-12-01), None
patent: 797980 (1997-10-01), None
patent: 1 176 140 (2002-01-01), None
patent: 760750 (1956-11-01), None
patent: 6-298732 (1994-10-01), None
patent: 6-298732 (1995-11-01), None
patent: 2000-95767 (2000-04-01), None
patent: 2001-143635 (2001-05-01), None
patent: 91/05761 (1991-05-01), None
patent: 91/18902 (1991-12-01), None
patent: 94/27986 (1994-12-01), None
patent: 95/11885 (1995-05-01), None
patent: 96/30014 (1996-10-01), None
patent: 97/44036 (1997-11-01), None
patent: 97/44337 (1997-11-01), None
patent: 97/48697 (1997-12-01), None
patent: 98/2420 (1998-01-01), None
patent: 98/18765 (1998-05-01), None
patent: 98/20007 (1998-05-01), None
patent: 98/22452 (1998-05-01), None
patent: 98/24771 (1998-06-01), None
patent: 98/28269 (1998-07-01), None
patent: 98/45255 (1998-10-01), None
patent: 99/15505 (1999-04-01), None
patent: 99/41239 (1999-08-01), None
patent: 99/45002 (1999-09-01), None
patent: 99/64423 (1999-12-01), None
patent: 00/06085 (2000-02-01), None
patent: 00/07980 (2000-02-01), None
patent: 00/07991 (2000-02-01), None
patent: 00/42213 (2000-07-01), None
patent: 00/47558 (2000-08-01), None
patent: 01/21615 (2001-03-01), None
patent: 01/28993 (2001-04-01), None
Eur. J. Med. Chem. Chim. Ther., (1985), 20 (2), pp. 187-189.
Chemical Abstracts, vol. 92, Abstract No. 128647.
J. Pharm. Sci., (1975), 64 (6), pp. 1001-1005.
Chemical Abstracts, vol. 52, Abstract No. 13718c-e.
Chemical Abstracts, vol. 98, Abstract No. 53609.
J. Heterocycl. Chem., (1991), 28 (5), pp. 1309-1313.
J. Heterocycl. Chem., (1987), 24 (6), pp. 1589-1594.
Chemical Abstracts, vol. 106, ABstract No. 67157.
J. Svoboda et atl., “Synthesis and Biological Evaluation of New Antiinflammatory 1-Benzolhiophene-2-Carboxanilides”, Collection of Czechoslovak Chemical Communications, vol. 65, No. 7, pp. 1082-1092, 2000.
K. L. Milkiewicz et al., “The Design, Synthesis and Activity of Non-ATP Competitive Inhibitors of pp60°srcTyrosine Kinase. Part 2: Hydroxyindole Derivatives”, Bioorganic & Medicinal Chemistry Letters, vol. 10, No. 5, pp. 483-486, Mar. 2000.
A. Taudou et al., “Recherche d'activite anti-parasitaire de carboxamido-2-benzopyrones-4”, European Journal of Medicinal Cehmistry, vol. 22, pp. 583-585, 1987.

Affiliated with

Also associated with

Rating

Fused bicyclic amide compounds and medicinal use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fused bicyclic amide compounds and medicinal use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fused bicyclic amide compounds and medicinal use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3524818