Forskolin compounds

Details Forskolin compounds Forskolin compounds

1989-05-30

1990-09-04

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31192

Patent

active

049546422

ABSTRACT:
This invention relates to forskolin derivatives, their physiologically acceptable salts, and a process for producing these compounds. The forskolin derivative is represented by the general formula ##STR1## wherein; I. when R.sup.1 is hydrogen and R.sup.4 is vinyl, ethyl, or cyclopropyl,

REFERENCES:
patent: 4088659 (1978-05-01), Bhat
patent: 4134986 (1979-01-01), Bajwa et al.
patent: 4639443 (1987-01-01), Kosley, Jr. et al.
patent: 4639446 (1987-01-01), Kosley, Jr. et al.
Metzger et al, "The Positive Inotropic-Acting Forskolin, a Potent Adenylatecyclase Activator", Arzneimittel-Forschung, vol. 31, pp. 1248-1250, (1981).
Bhat Journal of Medicinal Chemistry, "The Antihypertensive and Positive Inotropic Diterpene Forskolin: Effects of Structural Modifications on Its Activity" vol. 26, pp. 486-492, (1983).

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