Fluorinated phenyl thiophenyl derivatives and their use for...

Details Fluorinated phenyl thiophenyl derivatives and their use for... Fluorinated phenyl thiophenyl derivatives and their use for...

2006-05-09

2006-05-09

Davis, Brian (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C514S612000, C514S649000, C514S653000

Reexamination Certificate

active

07041851

ABSTRACT:
This invention relates to novel fluorinated phenyl thiphenyl (also named diarylsulfide) derivatives and their use in Positron Emission Tomagraphy (PET) imaging of Serotonin Transporters (SERTS). The present invention also provides diagnostic compositions comprising the novel compounds of the present invention, and a pharmaceutically acceptable carrier or diluent. The invention further provides a method of imaging SERTS, comprising introducing into a patient a detectable quantity of a labeled compound of the present invetion, or a pharmaceutically acceptable salt, ester, amide or prodrug thereof.

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