Fluorinated benzothiadiazine compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C544S012000

Reexamination Certificate

active

11041495

ABSTRACT:
Compounds of formula (I):wherein:RFrepresents monofluoro- or polyfluoro-alkyl or monofluoro- or polyfluoro-cycloalkylalkyl,R1represents hydrogen or a group selected from alkylaminocarbonyl and optionally substituted alkyl,R2represents hydrogen, halogen or a group selected from cycloalkyl and optionally substituted alkyl,R3to R6, which may be the same or different, each represent an atom or group selected from hydrogen, halogen, nitro, cyano, alkylsulphonyl, hydroxy, alkoxy, optionally substituted alkyl and optionally substituted amino,its optical isomers when they exist, and also their addition salts with a pharmaceutically acceptable acid or base.Medicinal products containing the same which are useful as AMPA modulators.

REFERENCES:
Alt et al. Current Pharmaceutical Design, 2005, 11, 1511-1527.
Black et al Psychopharmacology (2005) 179: 154-163.

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