Flow cytometer

Details Flow cytometer Flow cytometer

1993-02-08

1994-11-22

Harvey, Jack B.

Boots, shoes, and leggings

356317, 356442, 36441308, G01N 1500

Patent

active

053674740

ABSTRACT:
A flow cytometer includes a plurality of detectors for providing voltage pulse signals over a four decade range as particles pass through an illuminated detection station. Each voltage pulse signal is processed and provided to a first sample and hold for storage. Thereafter, the value in the first sample and hold is amplified by one or thirty-two, depending upon its magnitude, and stored in a second sample and hold for subsequent provision to a sixteen bit analog to digital convertor (ADC), one signal at a time. The first sample and hold is then free to store a new value while the old value is awaiting provision to the ADC. The ADC converts the signal received from the second sample and hold to a fifteen bit digital signal and uses the sixteenth bit to manifest whether the signal stored in the second sample and hold was amplified by thirty-two.

REFERENCES:
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patent: 3657537 (1972-04-01), Wheeless, Jr.
patent: 3761889 (1973-09-01), Hallee et al.
patent: 3818200 (1974-06-01), Pilhofer
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patent: 4038556 (1977-07-01), Auer et al.
patent: 4348107 (1982-09-01), Leif
patent: 4667830 (1987-05-01), Nozake, Jr.
patent: 4778593 (1988-10-01), Yamashita
patent: 4987539 (1991-01-01), Moore et al.
patent: 5166675 (1992-11-01), Amemiya et al.

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