Field-release mass spectrometry

Radiant energy – Ionic separation or analysis – With sample supply means

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436155, 436173, H01J 4904

Patent

active

059526548

ABSTRACT:
Methods of releasing and analyzing substrates such as DNA, comprising: a) covalently or ligandly binding substrate to a first electrode via a release group, which release group is cleavable in response to applied energy; b) introducing an electrical field so as to establish a charge potential between the first electrode and a second electrode separated by a vacuum or gas phase from the first electrode, the strength of such field sufficient to bristle said covalently-bound or ligandly-bound substrate; and c) applying sufficient energy directly to the release group to cleave the release group and release the substrate into a vacuum or gas phased

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