Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1990-06-14
1991-09-03
Weimar, Elizabeth C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 691, 4351723, 4352523, 43525233, 4352402, 4353201, 435 91, 536 27, 935 11, 935 27, 935 29, 935 56, 935 60, 935 70, 935 73, 935 32, C12N 1503, C12N 1506, C12N 121, C12N 510, C12N 1512, C12P 2102, C07H 1512
Patent
active
050454552
ABSTRACT:
Methods and compositions are provided for recombinant DNA production of Factor VIIIC and truncated derivatives thereof. Based on amino acid sequences, probes are developed for isolating messenger RNA, cDNA and/or chromosomal DNA encoding for Factor VIIIC. The Factor VIIIC gene in its entirety, a fragment thereof, or a cDNA is then used for expression of Factor VIIIC in a host.
The bacteriophage .lambda.FVIII23D containing the 14.43kb EcoRI fragment was deposited at the A.T.C.C. on Jan. 4, 1984 and given Accession No. 40094. Also, the vector pSVF8-200 was deposited at the A.T.C.C. on July 17, 1985 and given Accession No. 40190.
REFERENCES:
patent: 4361509 (1982-11-01), Zimmerman et al.
patent: 4419446 (1983-12-01), Howley et al.
patent: 4649132 (1987-03-01), Zimmerman et al.
patent: 4657894 (1987-04-01), Zimmerman et al.
patent: 4757006 (1988-07-01), Toole, Jr. et al.
Bock et al, Nucleic Acids Research, vol. 10, pp. 8113-8125 (1982).
Jaye et al, Nucleic Acid Research, vol. 11, pp. 2325-2335, Apr. 25, 1983.
Ginsburg et al., (1985) Science 228:1401-1406.
Kurachi et al., (1982) Proc. Natl. Acad. Sci. U.S.A. 79:6461-6464.
Maniatis et al., Molecular Cloning: A Laboratory Manual, pp. 224-228 (1982).
Bloom (1983) Nature 303:474-475.
Muller et al., (1981) Blood 58:1000-1006.
Muller et al., (1982) Chemical Abstracts vol. 96, No. 5, p. 480 (Abstract No. 33095v).
Maddox (1983) Nature 306:528.
Rotblat et al., (1984) Biological Abstracts 77:4443 (Abstract No. 40713).
Rotblat et al., (1983) J. Lab. Clin. & Med. 101:736-746.
Hybritech Data Sheet (Catalogue #0432) (1982).
Fulcher et al., (1983) Blood 61:807-809.
Fulcher et al., (1983) Chemical Abstracts vol. 98, No. 21, p. 450 (Abstract No. 176896j).
Fass et al., (1982) Blood 59:594-600.
Kaufman et al., (1982) Molecular and Cellular Biology 2:1304-1319.
Fay et al., (1982) Proc. Natl. Acad. Sci. 79:7200-7204.
Choo et al., (1982) Nature 299:178-180.
Chan et al., (1984) Chemical Abstracts vol. 100, p. 214 (Abstract No. 63605e).
Rotblat et al., (1985) Biochemistry 24: 4294-4300.
Fulcher et al. (1982) Proc. Natl. Acad. Sci. U.S.A. 79:1648-1652.
Tuddenham et al. (1979) J. of Lab. Clin. Med. 93:40-53.
Austen (1979) British J. Menatology 43:669-674.
Weinstein et al. (1981) Proc. Natl. Acad. Sci. U.S.A. 78:5137-5141.
Kuo et al., Abstracts for IX Int. Cong. Thrombosis & Hemostasis, (Copenhagen, Jul. 1983).
Gitschier et al. (1984) Nature 312:326-330.
Wood et al. (1984) Nature 312:330-337.
Vehar et al. (1984) Nature 312:337-342.
Toole et al. (1984) Nature 312:342-347.
Burke Rae L.
Caput Daniel
Favaloro Jennifer M.
Kuo George
Masiarz Frank
Blackburn Robert P.
Chiron Corporation
Green Grant D.
Low Christopher S. F.
Weimar Elizabeth C.
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